Muhammad Mahmoud Khalil Museum is located in Doqqui, near Cairo Sheraton Hotel. Built in 1915 in the French style, the museum was once a palace that belonged to Mohammed Mahmoud Khalil, a statesman, a cabinet minister and a Speaker of the Senate. The palace was the residence of Mohammed Khalil’s family and the seat of his invaluable art collection until 1960. In accordance with the will drawn up by the wife of Mohammed Mahmoud Khalil, the palace was inaugurated as a museum on 23rd July 1962 bearing the name of Mohammed Mahmoud Khalil and his wife Emiline Lock. The ground, first and second floors of the palace all are used as the museum’s gallery. The basement houses the administrative offices, the Library, the Information Centre and a big lecture theatre. Among the museum's exhibits is a collection of masterpieces of great Europeans mainly of the 19th century. However, the majority of the museum’s 208 works feature the Impressionist School.

The great artists represented among the assets of Mohammed Mahmoud Khalil and his wife include Paul Gauguin, Auguste Renoir, Vincent Van Gogh, Claude Monet, John Jongkind and Charles Francois Daubigny. Additionally, the museum’s exhibits include large-size bronze, marble and gypsum statues skillfully made by great sculptors of the 19th century such as Auguste Rodin, Jean-Baptiste Carpeaux, Louis Antoine Barye and Charles Cordier. It also preserves a priceless collection of vases made in France, China, Japan and Iran, as well as a big collection of elaborately-made miniature works of art by Chinese artists in precious stones, crystal de Roch, emerald and coral. Moreover, there is a rare collection of small Japanese-styled boxes on display in the museum.