Queen Ahhotep

She was Ahmose's mother, whose large outer coffin was found in the Deir el-Bahari royal cache. According to her titles on that coffin, she was a king's daughter, a king's sister, great royal wife, and a king's mother. It is highly probable that Ahhotep was honored later by her son for pacifying Upper Egypt and expelling rebels. She continued to function as a king's mother well into the reign of Amenhotep I.

 Queen Ahmose-Nefertari 

Not long after 18 years of Ahmose's reign, Ahmose-Nefertari appeared on the scene of historical events. She might have been the daughter of Queen Ahhotep. Her stela at Karnak is the first known monument on which Ahmose-Nefertari is figured. On the stela, she is described as a king's daughter, a king's sister, a king's great wife, god's wife of Amun, and a mistress of Upper and Lower Egypt. Both Ahmose and Ahmose-Nefertari are depicted together with their son, Prince Ahmose-ankh. Only a few years after this inscription was made, in the 22nd year, Ahmose-Nefertari claimed the title of a king's mother, although it is not known whether this title refers to her being the mother of Ahmose-ankh or Amenhotep. In any case, the queen outlived her husband Ahmose and even her son Amenhotep I, and still held the position of god's wife of Amun in the reign of Thutmosis I.

 Queen Nefertiti 

 Nefertiti was the main royal wife of Akhenaten, she had produced six daughters, but no son, and although she never lost her prime position as 'great royal wife', a second wife of Akhenaten had appeared on the scene at Akhetaten. It has often been speculated that she was a Mitannian princess, but her name Kiya is a perfectly normal Egyptian one and it does not indicate that she was of a foreign origin. She was given the title 'Greatly Beloved Wife of the King', which distinguishes her from any other ladies in the royal harem. Shortly before the 12th year of the King's reign, she suddenly disappears from the monuments, and her name was erased from the inscriptions and replaced by those of Akhenaten's daughters, most frequently that of Meritaten. Since even the funerary equipment prepared for her, including a magnificent coffin, was adapted for a different royal person, it is most likely that Kiya at some point fell from grace, perhaps because she had become too much of a rival to Nefertiti after she had given birth perhaps to a male heir.
There is no hard evidence to support this opinion, but a single inscription from about this time reads 'the King's bodily son, his beloved, Tutankhaten', who is the future Tutankhamun, who was almost certainly a son of Akhenaten but not of Nefertiti. Nefertiti's influence increased even further during the later part of the reign, when she became the official co-regent of her husband as Neferneferuaten with the throne name 'Ankh (et) kheperure'. Her role as queen consort was taken over by her eldest daughter, Merutaten. Whether or not Nefertiti survived Akhenaten, who died aging 17, is uncertain